High Throughput Process Development Market Overview and Analysis Market Overview
The high-through-process development market is currently valued at USD 25.56 billion in the year 2022 and is expected to register a CAGR of 14.4% over the forecast period 2022-2030.
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High Throughput Process Development (HTPD) is a scientific process that allows automated testing of large numbers of chemical and/or biological compounds for a specific biological target, thereby accelerating the drug development process by screening large compounds.
The growth of the high-throughput process development market has been driven due to increased expenditure and advancement in the R&D market. The increased expenditure in the R&D segment led the scientists to test thousands of compounds. The automation techniques have led to testing a large number of compounds, without much human labor.
High Throughput Process Development Market Latest Trends
High throughput process development is mainly used for conducting various genetic, chemical, and pharmacological tests that aid the drug discovery process starting from drug design to drug trials and other drug interactions. This process involves control software, various devices to handle liquids, and other detectors, which help to rapidly identify active compounds, genetic interactions, and other biomolecular interactions. However, most of these techniques need expertise and software that can handle and store multiple sets of data at a rapid pace, the lack of which is anticipated to inhibit growth prospects.
Segmentation:
The high throughput process development market is segmented
Products and Services
- Software
- Instruments
- Services
- Consumables
Technology
- Chromatography
- Ultraviolet light
- Other Technologies
End-Users
- Biopharmaceuticals
- Contract Research Organizations
- Other End-Users
Geography
- North America
- Europe
- Asia-Pacific
- Middle East
- Africa
- South America
The report offers the value (in USD million) for the above segments.
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Market Drivers
Open Access to High-throughput Screening Laboratories and Technological Advancements in HTS
Thus, analysis of such a large number of compounds has led scientists to analyze a large amount of data using extensive automation techniques which have accelerated the drug discovery process. For instance, in 2021, an article titled “Integrative approaches for mRNA and microRNA high-throughput data” published in the journal Computational and Biotechnology Journal states that the development of infrastructure and technology is the reason for the expansion of the high throughput process development market. In biomanufacturing, the high throughput process development tools, and technology are used for simpler and faster development of the downstream chromatography process. High throughput tools can be used for creating chromatography conditions and media developments which can save much time for process developers. Also due to the rising demand for the manufacturing of monoclonal antibodies high throughput process development market has shown a tremendous increase. The high throughput process development method is also used to test the compounds in functional and binding assays. Thus, R&D investments and advancements have driven the high throughput process development market.
Therefore, owing to the aforementioned factors the studied market is anticipated to witness growth over the analysis period. The main limitation of this high-throughput process development market is a high investment cost in many R&D techniques and infrastructure, which may slow down its market growth.
Market Restraints:
High Capital Investment and Need for Extensive Automation Techniques
Automation eliminates human error from the manufacturing process, which is essential for production assembly systems. Automation systems are quite expensive as a result the cost of HTS products may increase which may slow down the growth of the studied market.
COVID-19 and Russian War Impact on High Throughput Process Development Market
The emergence of COVID-19 has led to the health crisis that the world has witnessed and had an unprecedented impact on various industries specifically the healthcare and biotechnology industries. Strict regulations and restrictions imposed by the government have led to slowing down the work in industries. In just a few weeks, after the COVID-19 outbreak, scientists have discovered a list of molecules to overcome this crisis. For instance, according to the journal Human Vaccines and Therapeutics in 2021, more than 70 vaccines are in development for COVID-19 treatment, and 20 of them are in phase-3 trials to overcome the COVID-19 crisis. High-throughput process development methods help in vaccine development. For instance, in the Journal, of Drug Discovery Today, 2021 an article titled High-throughput screening assays for SARS-CoV-2 drug development: current status and future directions summarizes that the high throughput process development platform includes massive parallel sequencing or next-generation sequencing which has led to the production of millions of nucleic acid bases within a single sequencing reaction. The huge data generated from this reaction has the potential to detect nucleic acid that may be present at a low level of a complex biological system. This helps in the easy detection, identification, and checking of the permeability, metabolic activity, and cytotoxicity of antigens at the metabolic and cellular levels. The data obtained from this screening process thereby accelerate the development of drugs and vaccines against the targeted bacteria or virus. Thereby easing the vaccine development process.
Segmentation Trends
The Chromatography Technology Segment Accounted for the Largest Share Of The Global Market And Witnessed Significant Growth
High-throughput process development (HTPD) is the type of process that reduces development time and increases the amount of data accessible for quality-by-design (QbD) approaches. The chromatographic separation method has been accomplished by performing a series of experiments using either manual or automated chromatography systems. High-throughput process development (HTPD) platform involves the integration of miniaturization, automation, and parallelization and provides a systematic approach for time and resource-efficient chromatography process development. Owing to the advantages offered by chromatography over other technological segments such as high selectivity, and high flow rate, extensive removal of impurities such as host cell protein, DNA, and cell culture ultimately drives the market growth.
For instance, in an article published in Wiley Analytical Journal in 2021, an increase in the prevalence of cancer is expected to drive the growth of the chromatography segment. As adoption of chromatography technology in pharmaceutical R&D in cancer treatment is expected to provide growth opportunities for global market players. Also, the development of novel solvent systems in chromatography is driving the growth of this segment. In the purification of drug molecules, the rapid ongoing demand for chromatography for testing purposes is driving growth. The high efficiency and accuracy of chromatography are increasing its use in forensics and disease testing.
Therefore, the chromatography segment is expected to witness significant growth over the forecast period due to the abovementioned factors.
High Throughput Process Development Market Segment is Expected to Witness Significant Growth Over the Forecast Period
The growing burden of chronic diseases and increasing investments in research and development activities are the major factors driving the biopharmaceutical segment. The biopharmaceuticals will grow due to increasing chronic disease incidences, well-established biopharmaceutical companies' presence, and an increase in biotech companies. The rising geriatric population and increased research and developments in the country also drive segment’s growth.
High Throughput Process Development Market Target Identification Segment is Expected to Witness High Growth Over the Forecast Period
High throughput and other compound screens are developed and run to identify molecules that interact with the drug target, chemistry programs are run to improve the potency, selectivity, and physiochemical properties of the molecule, and data continue to be developed to support the hypothesis that intervention at the drug target will have efficacy in the disease state. It is this series of activities that is the subject of intense activity within the pharmaceutical industry and increasingly within academia to identify candidate molecules for clinical development.
North America is Expected to Dominate the High Throughput Process Development Market
North America is expected to dominate the market owing to factors such as the easy availability of technologically advanced products, well-established healthcare infrastructure, and a strong network of suppliers. The rising demand for products with decreasing product development timelines is driving its production of biologics, collective pressure leading to a decrease in the cost of manufacture of biological materials, and presence of key product launches, high concentration of market players, and manufacturer's presence in the United States are some of the factors driving the growth of the high throughput process development market in the country.
The increase in the production of major biologics by top manufacturing companies such as AstraZeneca and GSK in the United States has embarked on the biologics wave which has led to increased production of biologics. This resulted in decreased costs and easy accessibility to patients. Also, biologics enter into therapeutic areas such as asthma, allergy, and dyslipidemia thereby more people are opting for the biological product over traditional therapy for disease treatment. For instance, the World Health Organization 2022, and another instance Centers for Disease Control and Prevention 2021, account for 45 million cases of asthma, and 94 million cases of dyslipidemia in the United States respectively. The high prevalence population present in the United States and the majority of this prevalent population opting for biologics for treatment have driven the market for biologics.
Scientific advancement by the key market players in the United States has enabled biosimilar developers to improve the molecule significantly. Technologies such as novel screening methods have aided the detection and replacement of immunogenic sections of proteins, also a better understanding of structure/solution stability, and stress tests have improved the temperature stability and shelf-life of biosimilar products. Therefore, owing to the aforementioned factors the growth of the studied market is anticipated in the North America Region.
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Competitive Landscape of High Throughput Process Development Market
The high-through-process development market is consolidated in nature due to the presence of fewer companies operating globally as well as regionally. The competitive landscape includes an analysis of a few international as well as local companies that hold the market shares and are well known as
- GE Healthcare
- Merck KgAa
- Danaher Corporation
- Thermo Fisher Scientific Inc.
- Bio Rad Laboratories Inc.
- Sartorius AG
- Agilent Technologies
- Luminex Applikon
- Tecan Trading AG
- Eppendorf AG
- PerkinElmer Inc.
Recent Developments
In 2022, the Scripps Research Institute collaborated with scientists from the University of North Carolina at Chapel Hill and Virginia Commonwealth University to map the structure of the key receptor in the human brain that moderate pleasure, pain, addiction, depression, psychosis, and related conditions using in vivo high throughput process development method.
In April 2021, the advancement of high-throughput process development and computational methodologies are fostered to leverage the design of novel enzyme biocatalysts for industrial bioprocess. These potent and innovative techniques of enzyme engineering deliver outstanding opportunities for tailoring industrially important enzymes for the versatile production of biochemicals.
Frequently Asked Questions (FAQ) :
Q1. How big is the High Throughput Process Development Market ?
The High Throughput Process Development Market is currently valued at USD 25.56 billion in the year 2022 and is expected to register a CAGR of 14.4% over the forecast period 2022-2030.
Q2. What is the CAGR of the What is the Growth Rate of the Mango Market ?
The High Throughput Process Development Market is expected to register a CAGR of 14.4% over the forecast period 2022-2030.
Q3. What segments are covered in theHigh Throughput Process Development Market Report?
The segments covered by High Throughput Process Development Market is By Ptoduct and Service, By technology, End User and Geography.
Q4. Which Region is expected to hold the higest Market share?
North America is expected to dominate the Market over the forecast period
Study Assumptions and Market Definition
Scope of the Study
RESEARCH METHODOLOGY
EXECUTIVE SUMMARY
MARKET DYNAMICS
Market Overview
Market Drivers
Open Access to High-throughput Screening Laboratories and Technological Advancements in HTS
Increasing Usage in Universities and Research Centers
Market Restraints
High Capital Investment and Need for Extensive Automation Techniques
Porter's Five Force Analysis
Threat of New Entrants
Bargaining Power of Buyers/Consumers
Bargaining Power of Suppliers
Threat of Substitute Products
Intensity of Competitive Rivalry
MARKET SEGMENTATION (Market Size by Value - USD million)
By Products and Services
Instruments
Reagents and Kits
Services
By End User
Pharmaceutical and Biotechnology Firms
Academia and Research Institutes
Contract Research Organizations
Geography
North America
United States
Canada
Mexico
Europe
Germany
United Kingdom
France
Italy
Spain
Rest of Europe
Asia-Pacific
China
Japan
India
Australia
South Korea
Rest of Asia-Pacific
Middle East and Africa
GCC
South Africa
Rest of Middle East and Africa
South America
Brazil
Argentina
Rest of South America
COMPETITIVE LANDSCAPE
Company Profiles
Agilent Technologies Inc.
Axxam SpA
Beckman Coulter Inc.
Bio-Rad Laboratories Inc.
Danaher Corporation
GE Healthcare
Merck KGaA
PerkinElmer Inc.
Tecan Group Ltd
Thermo Fisher Scientific Inc.
MARKET OPPORTUNITIES AND FUTURE TRENDS
Data Library Research are conducted by industry experts who offer insight on industry structure, market segmentations technology assessment and competitive landscape (CL), and penetration, as well as on emerging trends. Their analysis is based on primary interviews (~ 80%) and secondary research (~ 20%) as well as years of professional expertise in their respective industries. Adding to this, by analysing historical trends and current market positions, our analysts predict where the market will be headed for the next five years. Furthermore, the varying trends of segment & categories geographically presented are also studied and the estimated based on the primary & secondary research.
In this particular report from the supply side Data Library Research has conducted primary surveys (interviews) with the key level executives (VP, CEO’s, Marketing Director, Business Development Manager and SOFT) of the companies that active & prominent as well as the midsized organization
FIGURE 1: DLR RESEARH PROCESS
Extensive primary research was conducted to gain a deeper insight of the market and industry performance. The analysis is based on both primary and secondary research as well as years of professional expertise in the respective industries.
In addition to analysing current and historical trends, our analysts predict where the market is headed over the next five years.
It varies by segment for these categories geographically presented in the list of market tables. Speaking about this particular report we have conducted primary surveys (interviews) with the key level executives (VP, CEO’s, Marketing Director, Business Development Manager and many more) of the major players active in the market.
Secondary ResearchSecondary research was mainly used to collect and identify information useful for the extensive, technical, market-oriented, and Friend’s study of the Global Extra Neutral Alcohol. It was also used to obtain key information about major players, market classification and segmentation according to the industry trends, geographical markets, and developments related to the market and technology perspectives. For this study, analysts have gathered information from various credible sources, such as annual reports, sec filings, journals, white papers, SOFT presentations, and company web sites.
Market Size EstimationBoth, top-down and bottom-up approaches were used to estimate and validate the size of the Global market and to estimate the size of various other dependent submarkets in the overall Extra Neutral Alcohol. The key players in the market were identified through secondary research and their market contributions in the respective geographies were determined through primary and secondary research.
Forecast Model
