The medical industry is mainly focused on creating new paths for medical treatment by using advanced technologies. Bone grafts have been used for bone regeneration, structure restoration, and pain relief for decades. Bone grafts have helped many patients in recovering from critical conditions. The treatment of injuries in the bones and joints is a key driver of demand within the global bone grafts and substitutes market. The rising importance of premium dental treatments such as treatments for fractures in and around the dental cavity. Growing investments in dental technologies in recent years. These are some prominent factors for the growth of the bone graft and substitutes market.
The rising medical condition such as anemia and weakening of bones in the geriatric population. Sports injuries often result in the weakening of bones. Therefore, treatment for bone disorders and injuries has created huge opportunities for market growth. Minimally invasive surgeries are being adopted for the treatment of a varied range of bone disorders. It also stated that about 400,000 spinal fusion cases were done in the U.S. yearly. Such factors positively impact the growth of the market.
Spine fusion, long bone fracture, open-wedge tibial osteotomy, oral and maxillofacial surgery, and periodontal treatments. These are some areas where lucrative opportunities are present for the bone grafts and substitutes market.
Bone Graft and Substitutes Market Segment Overview
The allograft segment is the fastest-growing segment in the market. Allografts have both osteoinductive and osteoconductive properties, hence it serves as a substitute for autografts. Allografts are available in different shapes and sizes that can be processed in various forms such as chips and others. These are commonly used in spine, hip, and knee areas. All these factors are likely to fuel the allografts segment of the bone grafts and substitutes market during the forecast period. According to the Centers for Disease Control and Prevention (CDC), nearly 51.4 million inpatient surgeries were carried out in the U.S. in 2014. Of these, 719,000 were total knee replacements and 332,000 were total hip replacements.
Bone Graft and Substitutes Market Regional Overview
North America dominated the global bone grafts and substitutes market. This is due to a highly developed health care sector and a rise in awareness among health care providers about bone grafts and substitutes. In addition, favorable government laws regarding the usage of bone graft & substitutes drive the growth of the market in the region. Furthermore, technological developments and growth in the adoption of advanced bone grafts and substitute products are anticipated to boost the bone grafts and substitutes market in the Asia Pacific, Latin America, and Middle East & Africa during the forecast period.
Bone Graft and Substitutes Market Competitor overview
The market leaders are mainly focused on product launches, partnerships, and acquisitions to improve the market share.
=> For instance, in October 2019, McGill University developed a biocompatible and toughened multilayered bone graft for the treatment of large bone defects.
=> In March 2020, Orthofix International N.V acquired the FITBONE system. The transaction involves other applications such as the FITSPINE system for a fusion-less operation to treat scoliosis.
=> In November 2019, NuVasive, Inc. received FDA approval for the CoRoent Small Interlock system, which is used to treat adult patients suffering from spinal instability or cervical disc degeneration.
=> In September 2019, DePuy Synthes-a subsidiary of Johnson & Johnson Medical Devices Companies-introduced a CONDUIT interbody platform-a 3D printed implant with EIT cellular titanium technology for spine surgery.
Bone Graft and Substitutes Market, Key Players
· AlloSource
· DePuy Synthes
· Integra LifeSciences
· NuVasive, Inc.
· Stryker
· Wright Medical Group N.V.
· Xtant Medical
· Zimmer Biomet
· Baxter Healthcare Corporation
· Medtronic
Bone Graft and Substitutes Market Segmentation
Bone Graft and Substitutes Market, By Product
- Allografts
- Demineralized Bone Matrix (Dbm)
- Others
- Synthetic Bone Grafts
- Xenografts
Bone Graft and Substitutes Market, By Material
- Ceramic-Based
- Calcium Phosphate
- Calcium Sulfate
- Others
- Polymer-Based
- Polylactides
- Polyglycolides
- Polyurethanes
- Others
- Growth Factor-Based
- Cell-Based
- Others
Bone Graft and Substitutes Market, By End User
- Hospitals
- Orthopedic Clinics
- Others
- North America
- US
- Canada
- Europe
- UK
- Germany
- France
- Italy
- Spain
- Rest of Europe
- Asia-Pacific
- Japan
- China
- India
- Australia
- South Korea
- Rest of Asia-Pacific
- LAMEA
- Brazil
- Saudi Arabia
- UAE
- Rest of LAMEA
1. Introduction
- 1.1. Research Scope
- 1.2. Market Segmentation
- 1.3. Research Methodology
- 1.4. Definitions and Assumptions
2. Executive Summary
3. Market Dynamics
- 3.1. Market Drivers
- 3.2. Market Restraints
- 3.3. Market Opportunities
4. Key Insights
- 4.1. Key Emerging Trends – For Major Countries
- 4.2. Latest Technological Advancement
- 4.3. Regulatory Landscape
- 4.4. Industry SWOT Analysis
- 4.5. Porters Five Forces Analysis
5. Global Bone Graft and Substitutes Market Analysis (USD Billion), Insights and Forecast, 2020-2027
- 5.1. Key Findings / Summary
- 5.2. Market Analysis, Insights and Forecast – By Product
- 5.2.1. Allografts
- 5.2.1.1. Demineralized Bone Matrix (Dbm)
- 5.2.1.2. Others
- 5.2.2. Synthetic Bone Grafts
- 5.2.3. Xenografts
- 5.2.1. Allografts
- 5.3. Market Analysis, Insights and Forecast – By Material
- 5.3.1. Ceramic-Based
- 5.3.1.1. Calcium Phosphate
- 5.3.1.2. Calcium Sulfate
- 5.3.1.3. Others
- 5.3.2. Polymer-Based
- 5.3.2.1. Polylactides
- 5.3.2.2. Polyglycolides
- 5.3.2.3. Polyurethanes
- 5.3.2.4. Others
- 5.3.3. Growth Factor-Based
- 5.3.4. Cell-Based
- 5.3.5. Others
- 5.3.1. Ceramic-Based
- 5.4. Market Analysis, Insights and Forecast – By End User
- 5.4.1. Hospitals
- 5.4.2. Orthopedic Clinics
- 5.4.3. Others
- 5.5. Market Analysis, Insights and Forecast – By Region
- 5.5.1. North America
- 5.5.2. Latin America
- 5.5.3. Europe
- 5.5.4. Asia Pacific
- 5.5.5. Middle East and Africa
6. North America Bone Graft and Substitutes Market Analysis (USD Billion), Insights and Forecast, 2020-2027
- 6.1. Key Findings / Summary
- 6.2. Market Analysis, Insights and Forecast – By Product
- 6.2.1. Allografts
- 6.2.1.1. Demineralized Bone Matrix (Dbm)
- 6.2.1.2. Others
- 6.2.2. Synthetic Bone Grafts
- 6.2.1. Allografts
- 6.3. Market Analysis, Insights and Forecast – By Material
- 6.3.1. Ceramic-Based
- 6.3.1.1. Calcium Phosphate
- 6.3.1.2. Calcium Sulfate
- 6.3.1.3. Others
- 6.3.2. Polymer-Based
- 6.3.2.1. Polylactides
- 6.3.2.2. Polyglycolides
- 6.3.2.3. Polyurethanes
- 6.3.2.4. Others
- 6.3.3. Growth Factor-Based
- 6.3.4. Cell-Based
- 6.3.5. Others
- 6.3.1. Ceramic-Based
- 6.4. Market Analysis, Insights and Forecast – By End User
- 6.4.1. Hospitals
- 6.4.2. Orthopedic Clinics
- 6.4.3. Others
- 6.5. Market Analysis, Insights and Forecast – By Country
- 6.5.1. U.S.
- 6.5.2. Canada
7. Latin America Bone Graft and Substitutes Market Analysis (USD Billion), Insights and Forecast, 2020-2027
- 7.1. Key Findings / Summary
- 7.2. Market Analysis, Insights and Forecast – By Product
- 7.2.1. Allografts
- 7.2.1.1. Demineralized Bone Matrix (Dbm)
- 7.2.1.2. Others
- 7.2.2. Synthetic Bone Grafts
- 7.2.3. Xenografts
- 7.2.1. Allografts
- 7.3. Market Analysis, Insights and Forecast – By Material
- 7.3.1. Ceramic-Based
- 7.3.1.1. Calcium Phosphate
- 7.3.1.2. Calcium Sulfate
- 7.3.1.3. Others
- 7.3.2. Polymer-Based
- 7.3.2.1. Polylactides
- 7.3.2.2. Polyglycolides
- 7.3.2.3. Polyurethanes
- 7.3.2.4. Others
- 7.3.3. Growth Factor-Based
- 7.3.4. Cell-Based
- 7.3.5. Others
- 7.3.1. Ceramic-Based
- 7.4. Market Analysis, Insights and Forecast – By End User
- 7.4.1. Hospitals
- 7.4.2. Orthopedic Clinics
- 7.4.3. Others
- 7.5. Insights and Forecast – By Country
- 7.5.1. Brazil
- 7.5.2. Mexico
- 7.5.3. Rest of Latin America
8. Europe Bone Graft and Substitutes Market Analysis (USD Billion), Insights and Forecast, 2020-2027
- 8.1. Key Findings / Summary
- 8.2. Market Analysis, Insights and Forecast – By Product
- 8.2.1. Allografts
- 8.2.1.1. Demineralized Bone Matrix (Dbm)
- 8.2.1.2. Others
- 8.2.2. Synthetic Bone Grafts
- 8.2.3. Xenografts
- 8.2.1. Allografts
- 8.3. Market Analysis, Insights and Forecast – By Material
- 8.3.1. Ceramic-Based
- 8.3.1.1. Calcium Phosphate
- 8.3.1.2. Calcium Sulfate
- 8.3.1.3. Others
- 8.3.2. Polymer-Based
- 8.3.2.1. Polylactides
- 8.3.2.2. Polyglycolides
- 8.3.2.3. Polyurethanes
- 8.3.2.4. Others
- 8.3.3. Growth Factor-Based
- 8.3.4. Cell-Based
- 8.3.5. Others
- 8.3.1. Ceramic-Based
- 8.4. Market Analysis, Insights and Forecast – By End User
- 8.4.1. Hospitals
- 8.4.2. Orthopedic Clinics
- 8.4.3. Others
- 8.5. Market Analysis, Insights and Forecast – By Country
- 8.5.1. UK
- 8.5.2. Germany
- 8.5.3. France
- 8.5.4. Italy
- 8.5.5. Spain
- 8.5.6. Russia
- 8.5.7. Rest of Europe
9. Asia Pacific Bone Graft and Substitutes Market Analysis (USD Billion), Insights and Forecast, 2020-2027
- 9.1. Key Findings / Summary
- 9.2. Market Analysis, Insights and Forecast – By Product
- 9.2.1. Allografts
- 9.2.1.1. Demineralized Bone Matrix (Dbm)
- 9.2.1.2. Others
- 9.2.2. Synthetic Bone Grafts
- 9.2.3. Xenografts
- 9.2.1. Allografts
- 9.3. Market Analysis, Insights and Forecast – By Material
- 9.3.1. Ceramic-Based
- 9.3.1.1. Calcium Phosphate
- 9.3.1.2. Calcium Sulfate
- 9.3.1.3. Others
- 9.3.2. Polymer-Based
- 9.3.2.1. Polylactides
- 9.3.2.2. Polyglycolides
- 9.3.2.3. Polyurethanes
- 9.3.2.4. Others
- 9.3.3. Growth Factor-Based
- 9.3.4. Cell-Based
- 9.3.5. Others
- 9.3.1. Ceramic-Based
- 9.4. Market Analysis, Insights and Forecast – By End User
- 9.4.1. Hospitals
- 9.4.2. Orthopedic Clinics
- 9.4.3. Others
- 9.5. Market Analysis, Insights and Forecast – By Country
- 9.5.1. China
- 9.5.2. India
- 9.5.3. Japan
- 9.5.4. Australia
- 9.5.5. South East Asia
- 9.5.6. Rest of Asia Pacific
10. Middle East & Africa Bone Graft and Substitutes Market Analysis (USD Billion), Insights and Forecast, 2020-2027
- 10.1. Key Findings / Summary
- 10.2. Market Analysis, Insights and Forecast – By Product
- 10.2.1. Allografts
- 10.2.1.1. Demineralized Bone Matrix (Dbm)
- 10.2.1.2. Others
- 10.2.2. Synthetic Bone Grafts
- 10.2.3. Xenografts
- 10.2.1. Allografts
- 10.3. Market Analysis, Insights and Forecast – By Material
- 10.3.1. Ceramic-Based
- 10.3.1.1. Calcium Phosphate
- 10.3.1.2. Calcium Sulfate
- 10.3.1.3. Others
- 10.3.2. Polymer-Based
- 10.3.2.1. Polylactides
- 10.3.2.2. Polyglycolides
- 10.3.2.3. Polyurethanes
- 10.3.2.4. Others
- 10.3.3. Growth Factor-Based
- 10.3.4. Cell-Based
- 10.3.5. Others
- 10.3.1. Ceramic-Based
- 10.4. Market Analysis, Insights and Forecast – By End User
- 10.4.1. Hospitals
- 10.4.2. Orthopedic Clinics
- 10.4.3. Others
- 10.5. Market Analysis, Insights and Forecast – By Country
- 10.5.1. GCC
- 10.5.2. South Africa
- 10.5.3. Rest of Middle East & Africa
11. Competitive Analysis
- 11.1. Company Market Share Analysis, 2018
- 11.2. Key Industry Developments
- 11.3. Company Profile
- 11.4. AlloSource
- 11.4.1. Business Overview
- 11.4.2. Segment 1 & Service Offering
- 11.4.3. Overall Revenue
- 11.4.4. Geographic Presence
- 11.4.5. Recent Development
- 11.5. DePuy Synthes
- 11.6. Integra LifeSciences
- 11.7. NuVasive, Inc.
- 11.8. Stryker
- 11.9. Wright Medical Group N.V.
- 11.10. Xtant Medical
- 11.11. Zimmer Biomet
- 11.12. Baxter Healthcare Corporation
Data Library Research are conducted by industry experts who offer insight on industry structure, market segmentations technology assessment and competitive landscape (CL), and penetration, as well as on emerging trends. Their analysis is based on primary interviews (~ 80%) and secondary research (~ 20%) as well as years of professional expertise in their respective industries. Adding to this, by analysing historical trends and current market positions, our analysts predict where the market will be headed for the next five years. Furthermore, the varying trends of segment & categories geographically presented are also studied and the estimated based on the primary & secondary research.
In this particular report from the supply side Data Library Research has conducted primary surveys (interviews) with the key level executives (VP, CEO’s, Marketing Director, Business Development Manager and SOFT) of the companies that active & prominent as well as the midsized organization
FIGURE 1: DLR RESEARH PROCESS
Extensive primary research was conducted to gain a deeper insight of the market and industry performance. The analysis is based on both primary and secondary research as well as years of professional expertise in the respective industries.
In addition to analysing current and historical trends, our analysts predict where the market is headed over the next five years.
It varies by segment for these categories geographically presented in the list of market tables. Speaking about this particular report we have conducted primary surveys (interviews) with the key level executives (VP, CEO’s, Marketing Director, Business Development Manager and many more) of the major players active in the market.
Secondary ResearchSecondary research was mainly used to collect and identify information useful for the extensive, technical, market-oriented, and Friend’s study of the Global Extra Neutral Alcohol. It was also used to obtain key information about major players, market classification and segmentation according to the industry trends, geographical markets, and developments related to the market and technology perspectives. For this study, analysts have gathered information from various credible sources, such as annual reports, sec filings, journals, white papers, SOFT presentations, and company web sites.
Market Size EstimationBoth, top-down and bottom-up approaches were used to estimate and validate the size of the Global market and to estimate the size of various other dependent submarkets in the overall Extra Neutral Alcohol. The key players in the market were identified through secondary research and their market contributions in the respective geographies were determined through primary and secondary research.
Forecast Model
